S. 4525 — Securing Innovation and Research from Adversaries Act

This section prohibits recipients of federal research awards from using those funds for any research collaboration with entities on United States Government restricted entity lists—including the Entity List, Unverified List, SDN list, and specified Chinese military, semiconductor, biotechnology, and telecommunications lists—or with individuals associated with such entities. It directs the Office of Science and Technology Policy to issue government-wide implementation guidance and authorizes agency heads to grant case-by-case waivers when necessary for national security interests or essential scientific, public health, or national security purposes, subject to a report to Congress within 30 days.